טוען...
Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload
Iron-related disorders are among the most prevalent diseases worldwide. Systemic iron homeostasis requires hepcidin, a liver-derived hormone that controls iron mobilization through its molecular target ferroportin (FPN), the only known mammalian iron exporter. This pathway is perturbed in diseases t...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6307944/ https://ncbi.nlm.nih.gov/pubmed/30352047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122359 |
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