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Intravascular heavy chain-modification of hyaluronan during endotoxic shock

During inflammation, the covalent linking of the ubiquitous extracellular polysaccharide hyaluronan (HA) with the heavy chains (HC) of the serum protein inter alpha inhibitor (IαI) is exclusively mediated by the enzyme tumor necrosis factor α (TNFα)-stimulated-gene-6 (TSG-6). While significant advan...

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Publicat a:Biochem Biophys Rep
Autors principals: Ni, Kevin, Gill, Amar, Cao, Danting, Koike, Kengo, Schweitzer, Kelly S., Garantziotis, Stavros, Petrache, Irina
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307094/
https://ncbi.nlm.nih.gov/pubmed/30623115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.12.007
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