Rapid clearance of heavy chain-modified hyaluronan during resolving acute lung injury

BACKGROUND: Several inflammatory lung diseases display abundant presence of hyaluronic acid (HA) bound to heavy chains (HC) of serum protein inter-alpha-inhibitor (IαI) in the extracellular matrix. The HC-HA modification is critical to neutrophil sequestration in liver sinusoids and to survival duri...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Ni, Kevin, Gill, Amar, Tseng, Victor, Mikosz, Andrew M., Koike, Kengo, Beatman, Erica L., Xu, Cassie Y., Cao, Danting, Gally, Fabienne, Mould, Kara J., Serban, Karina A., Schweitzer, Kelly S., March, Keith L., Janssen, William J., Nozik-Grayck, Eva, Garantziotis, Stavros, Petrache, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984366/
https://ncbi.nlm.nih.gov/pubmed/29855321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0812-1
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