Advanced forms of MPNs are accompanied by chromosomal abnormalities that lead to dysregulation of TP53

The Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), including polycythemia vera (PV), essential thrombocythemia (ET), and the prefibrotic form of primary myelofibrosis (PMF), frequently progress to more overt forms of MF and a type of acute leukemia termed MPN-accelerated phase...

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Foilsithe in:Blood Adv
Main Authors: Marcellino, Bridget K., Hoffman, Ronald, Tripodi, Joseph, Lu, Min, Kosiorek, Heidi, Mascarenhas, John, Rampal, Raajit K., Dueck, Amylou, Najfeld, Vesna
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2018
Ábhair:
Myeloid Neoplasia
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306879/
https://ncbi.nlm.nih.gov/pubmed/30563882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018024018
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