Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms

Myeloproliferative neoplasms (MPN), including polycythemia vera, essential thrombocythemia, and primary myelofibrosis, have a propensity to evolve into accelerated and blast-phase disease (MPN-AP/BP), carrying a dismal prognosis. Conventional antileukemia therapy has limited efficacy in this setting...

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Udgivet i:Blood Adv
Main Authors: Rampal, Raajit K., Mascarenhas, John O., Kosiorek, Heidi E., Price, Leah, Berenzon, Dmitriy, Hexner, Elizabeth, Abboud, Camille N., Kremyanskaya, Marina, Weinberg, Rona Singer, Salama, Mohamed E., Menghrajani, Kamal, Najfeld, Vesna, Sandy, Lonette, Heaney, Mark L., Levine, Ross L., Mesa, Ruben A., Dueck, Amylou C., Goldberg, Judith D., Hoffman, Ronald
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2018
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306885/
https://ncbi.nlm.nih.gov/pubmed/30563881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018019661
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