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Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults

ADP-ribosylation is an important post-translational protein modification that regulates diverse biological processes, controlled by dedicated transferases, and hydrolases. Disruption in the gene encoding for MACROD2, a mono-ADP-ribosylhydrolase, has been associated to the Kabuki syndrome, a pediatri...

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Détails bibliographiques
Publié dans:Front Genet
Auteurs principaux: Lo Re, Oriana, Mazza, Tommaso, Vinciguerra, Manlio
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305994/
https://ncbi.nlm.nih.gov/pubmed/30619475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00654
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