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Mechanism of ADP-ribosylation removal revealed by the structure and ligand complexes of the dimanganese mono-ADP-ribosylhydrolase DraG

ADP-ribosylation is a ubiquitous regulatory posttranslational modification involved in numerous key processes such as DNA repair, transcription, cell differentiation, apoptosis, and the pathogenic mechanism of certain bacterial toxins. Despite the importance of this reversible process, very little i...

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Detalhes bibliográficos
Main Authors: Berthold, Catrine L., Wang, He, Nordlund, Stefan, Högbom, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732831/
https://ncbi.nlm.nih.gov/pubmed/19706507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905906106
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