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Mechanism of ADP-ribosylation removal revealed by the structure and ligand complexes of the dimanganese mono-ADP-ribosylhydrolase DraG

ADP-ribosylation is a ubiquitous regulatory posttranslational modification involved in numerous key processes such as DNA repair, transcription, cell differentiation, apoptosis, and the pathogenic mechanism of certain bacterial toxins. Despite the importance of this reversible process, very little i...

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Bibliographic Details
Main Authors: Berthold, Catrine L., Wang, He, Nordlund, Stefan, Högbom, Martin
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732831/
https://ncbi.nlm.nih.gov/pubmed/19706507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905906106
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