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High Levels of Eomes Promote Exhaustion of Anti-tumor CD8(+) T Cells
Eomes, a T-box transcription factor, is known important for both function and homeostasis of effector and memory T cells, but was recently also implicated in CD8(+) T cell exhaustion. However, whether and how Eomes might regulate effector functions or exhaustion of CD8(+) T cells, especially in the...
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| Veröffentlicht in: | Front Immunol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6305494/ https://ncbi.nlm.nih.gov/pubmed/30619337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02981 |
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