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High Levels of Eomes Promote Exhaustion of Anti-tumor CD8(+) T Cells

Eomes, a T-box transcription factor, is known important for both function and homeostasis of effector and memory T cells, but was recently also implicated in CD8(+) T cell exhaustion. However, whether and how Eomes might regulate effector functions or exhaustion of CD8(+) T cells, especially in the...

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Pubblicato in:Front Immunol
Autori principali: Li, Jing, He, Yi, Hao, Jing, Ni, Ling, Dong, Chen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305494/
https://ncbi.nlm.nih.gov/pubmed/30619337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02981
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