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Hirsutella Sinensis Fungus Regulates CD8(+) T Cell Exhaustion Through Involvement of T-Bet/Eomes in the Tumor Microenvironment

Background: Targeting exhausted T (Tex) cells is a promising strategy for anti-tumour treatment. Previously, we demonstrated that Hirsutella sinensis fungus (HSF) could significantly increase T cell infiltration and the effector T cell ratio in the tumor microenvironment, activating systemic immune...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Jin, Lu, Jin, Lushuai, Wu, Renjie, Liu, Xia, Zhu, Xinhai, Shou, Qiyang, Fu, Huiying
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820905/
https://ncbi.nlm.nih.gov/pubmed/33488388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.612620
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