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Chronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter

BACKGROUND: Our previous study has shown that cadmium (Cd) exposure is not only a risk factor for nasopharyngeal carcinoma (NPC), but also correlated with the clinical stage and lymph node metastasis. However, the underlying molecular events of Cd involved in NPC progression remain to be elucidated....

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Dettagli Bibliografici
Pubblicato in:Cancer Manag Res
Autori principali: Peng, Lin, Huang, Yi-Teng, Zhang, Fan, Chen, Jiong-Yu, Huo, Xia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304082/
https://ncbi.nlm.nih.gov/pubmed/30588112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S171200
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