SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma

BACKGROUND: Aberrant activation of the Wnt/β-catenin signaling pathway is an important factor in the development of nasopharyngeal carcinoma (NPC). Previous studies have demonstrated that the developmental gene sex-determining region Y (SRY)-box 1 (SOX1) inhibits cervical and liver tumorigenesis by...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Guan, Zhong, Zhang, Jialiang, Wang, Jing, Wang, Hefei, Zheng, Feimeng, Peng, Jieren, Xu, Yaodong, Yan, Min, Liu, Bing, Cui, Bai, Huang, Ying, Liu, Quentin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326525/
https://ncbi.nlm.nih.gov/pubmed/25427424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-257
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