SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway

Undifferentiation is a key feature of nasopharyngeal carcinoma (NPC), which presents as a unique opportunity for intervention by differentiation therapy. In this study, we found that SOX1 inhibited proliferation, promoted differentiation, and induced senescence of NPC cells, which depended on its tr...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lei, Xin-Xing, Liu, Yun, Wang, Jin-Xing, Cai, Qian, Yan, Min, He, Hui-Ping, Liu, Quentin, Long, Zi-Jie, Guan, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206110/
https://ncbi.nlm.nih.gov/pubmed/32382038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2513-1
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