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Chronic cadmium exposure aggravates malignant phenotypes of nasopharyngeal carcinoma by activating the Wnt/β-catenin signaling pathway via hypermethylation of the casein kinase 1α promoter

BACKGROUND: Our previous study has shown that cadmium (Cd) exposure is not only a risk factor for nasopharyngeal carcinoma (NPC), but also correlated with the clinical stage and lymph node metastasis. However, the underlying molecular events of Cd involved in NPC progression remain to be elucidated....

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Peng, Lin, Huang, Yi-Teng, Zhang, Fan, Chen, Jiong-Yu, Huo, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304082/
https://ncbi.nlm.nih.gov/pubmed/30588112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S171200
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