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A quasi-integral controller for adaptation of genetic modules to variable ribosome demand
The behavior of genetic circuits is often poorly predictable. A gene’s expression level is not only determined by the intended regulators, but also affected by changes in ribosome availability imparted by expression of other genes. Here we design a quasi-integral biomolecular feedback controller tha...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6303309/ https://ncbi.nlm.nih.gov/pubmed/30575748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07899-z |
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