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An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells

Synthetic biology has the potential to bring forth advanced genetic devices for applications in healthcare and biotechnology. However, accurately predicting the behavior of engineered genetic devices remains difficult due to lack of modularity, wherein a device’s output does not depend only on its i...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Jones, Ross D., Qian, Yili, Siciliano, Velia, DiAndreth, Breanna, Huh, Jin, Weiss, Ron, Del Vecchio, Domitilla
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656454/
https://ncbi.nlm.nih.gov/pubmed/33173034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19126-9
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