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An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells

Synthetic biology has the potential to bring forth advanced genetic devices for applications in healthcare and biotechnology. However, accurately predicting the behavior of engineered genetic devices remains difficult due to lack of modularity, wherein a device’s output does not depend only on its i...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jones, Ross D., Qian, Yili, Siciliano, Velia, DiAndreth, Breanna, Huh, Jin, Weiss, Ron, Del Vecchio, Domitilla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7656454/
https://ncbi.nlm.nih.gov/pubmed/33173034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19126-9
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