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Realizing ‘integral control’ in living cells: how to overcome leaky integration due to dilution?

A major problem in the design of synthetic genetic circuits is robustness to perturbations and uncertainty. Because of this, there have been significant efforts in recent years in finding approaches to implement integral control in genetic circuits. Integral controllers have the unique ability to ma...

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Podrobná bibliografie
Vydáno v:J R Soc Interface
Hlavní autoři: Qian, Yili, Del Vecchio, Domitilla
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832733/
https://ncbi.nlm.nih.gov/pubmed/29436515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0902
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