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Realizing ‘integral control’ in living cells: how to overcome leaky integration due to dilution?

A major problem in the design of synthetic genetic circuits is robustness to perturbations and uncertainty. Because of this, there have been significant efforts in recent years in finding approaches to implement integral control in genetic circuits. Integral controllers have the unique ability to ma...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J R Soc Interface
Asıl Yazarlar: Qian, Yili, Del Vecchio, Domitilla
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Royal Society 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832733/
https://ncbi.nlm.nih.gov/pubmed/29436515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0902
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