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Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

BACKGROUND. Increasing evidence indicates a role for EBV in the pathogenesis of multiple sclerosis (MS). EBV-infected autoreactive B cells might accumulate in the CNS because of defective cytotoxic CD8(+) T cell immunity. We sought to determine the feasibility and safety of treating progressive MS p...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan, Khanna, Rajiv
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302936/
https://ncbi.nlm.nih.gov/pubmed/30429369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124714
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