Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

BACKGROUND. Increasing evidence indicates a role for EBV in the pathogenesis of multiple sclerosis (MS). EBV-infected autoreactive B cells might accumulate in the CNS because of defective cytotoxic CD8(+) T cell immunity. We sought to determine the feasibility and safety of treating progressive MS p...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan, Khanna, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302936/
https://ncbi.nlm.nih.gov/pubmed/30429369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124714
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