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Acquisition of Polyfunctionality by Epstein-Barr Virus-Specific CD8(+) T Cells Correlates with Increased Resistance to Galectin-1-Mediated Suppression
Latent membrane antigen 1 and -2 (LMP-1/2)-specific CD8(+) T cells from newly diagnosed and relapsed Hodgkin's lymphoma (HL) patients display a selective functional impairment. In contrast, CD8(+) T cells specific for Epstein-Barr virus (EBV) nuclear proteins and lytic antigens retain normal T-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2687380/ https://ncbi.nlm.nih.gov/pubmed/19357166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00239-09 |
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