Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis

BACKGROUND: Soluble triggering receptor expressed on myeloid cells-2 (sTREM-2) is a marker of macrophage and microglial activation and is increased in the cerebrospinal fluid (CSF) in multiple sclerosis (MS). OBJECTIVE: To determine the relationships among sTREM-2, T cell activation, neuroaxonal dam...

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Detalhes bibliográficos
Publicado no:Mult Scler J Exp Transl Clin
Main Authors: Ioannides, Zara A, Csurhes, Peter A, Swayne, Andrew, Foubert, Philippe, Aftab, Blake T, Pender, Michael P
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2021
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182190/
https://ncbi.nlm.nih.gov/pubmed/34158970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/20552173211019772
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