T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response

BACKGROUND: Impaired T cell immunity in transplant recipients is associated with infection-related morbidity and mortality. We recently reported the successful use of adoptive T cell therapy (ACT) against drug-resistant/recurrent cytomegalovirus in solid-organ transplant recipients. METHODS: In the...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Smith, Corey, Corvino, Dillon, Beagley, Leone, Rehan, Sweera, Neller, Michelle A., Crooks, Pauline, Matthews, Katherine K., Solomon, Matthew, Le Texier, Laetitia, Campbell, Scott, Francis, Ross S., Chambers, Daniel, Khanna, Rajiv
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819118/
https://ncbi.nlm.nih.gov/pubmed/31415240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128323
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