Importin α5 Regulates Anxiety through MeCP2 and Sphingosine Kinase 1

Importins mediate transport from synapse to soma and from cytoplasm to nucleus, suggesting that perturbation of importin-dependent pathways should have significant neuronal consequences. A behavioral screen on five importin α knockout lines revealed that reduced expression of importin α5 (KPNA1) in...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Panayotis, Nicolas, Sheinin, Anton, Dagan, Shachar Y., Tsoory, Michael M., Rother, Franziska, Vadhvani, Mayur, Meshcheriakova, Anna, Koley, Sandip, Marvaldi, Letizia, Song, Didi-Andreas, Reuveny, Eitan, Eickholt, Britta J., Hartmann, Enno, Bader, Michael, Michaelevski, Izhak, Fainzilber, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302549/
https://ncbi.nlm.nih.gov/pubmed/30540948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.066
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