β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice

Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects, limiting their long-term usage. Here, we employ a bioinformatics screen to identify drugs for repurposing as anxiolytics. Comparison of drug-...

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Vydáno v:Cell Rep Med
Hlavní autoři: Panayotis, Nicolas, Freund, Philip A., Marvaldi, Letizia, Shalit, Tali, Brandis, Alexander, Mehlman, Tevie, Tsoory, Michael M., Fainzilber, Mike
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149471/
https://ncbi.nlm.nih.gov/pubmed/34095883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100281
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