Protective effects of voltage-gated calcium channel antagonists against zinc toxicity in SN56 neuroblastoma cholinergic cells

One of the pathological site effects in excitotoxic activation is Zn(2+) overload to postsynaptic neurons. Such an effect is considered to be equivalent to the glutamate component of excitotoxicity. Excessive uptake of Zn(2+) by active voltage-dependent transport systems in these neurons may lead to...

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Vydáno v:PLoS One
Hlavní autoři: Zyśk, Marlena, Gapys, Beata, Ronowska, Anna, Gul-Hinc, Sylwia, Erlandsson, Anna, Iwanicki, Adam, Sakowicz-Burkiewicz, Monika, Szutowicz, Andrzej, Bielarczyk, Hanna
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301650/
https://ncbi.nlm.nih.gov/pubmed/30571745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209363
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