Protective effects of voltage-gated calcium channel antagonists against zinc toxicity in SN56 neuroblastoma cholinergic cells

One of the pathological site effects in excitotoxic activation is Zn(2+) overload to postsynaptic neurons. Such an effect is considered to be equivalent to the glutamate component of excitotoxicity. Excessive uptake of Zn(2+) by active voltage-dependent transport systems in these neurons may lead to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zyśk, Marlena, Gapys, Beata, Ronowska, Anna, Gul-Hinc, Sylwia, Erlandsson, Anna, Iwanicki, Adam, Sakowicz-Burkiewicz, Monika, Szutowicz, Andrzej, Bielarczyk, Hanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301650/
https://ncbi.nlm.nih.gov/pubmed/30571745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209363
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