Early and Late Pathomechanisms in Alzheimer’s Disease: From Zinc to Amyloid-β Neurotoxicity

There are several systemic and intracerebral pathologic conditions, which limit provision and utilization of energy precursor metabolites in neuronal cells. Energy deficits cause excessive depolarization of neuronal cells triggering glutamate-zinc evoked excitotoxic cascade. The intracellular zinc e...

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Bibliografiske detaljer
Udgivet i:Neurochem Res
Main Authors: Szutowicz, Andrzej, Bielarczyk, Hanna, Zyśk, Marlena, Dyś, Aleksandra, Ronowska, Anna, Gul-Hinc, Sylwia, Klimaszewska-Łata, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2016
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357490/
https://ncbi.nlm.nih.gov/pubmed/28039593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-016-2154-z
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