Early and Late Pathomechanisms in Alzheimer’s Disease: From Zinc to Amyloid-β Neurotoxicity

There are several systemic and intracerebral pathologic conditions, which limit provision and utilization of energy precursor metabolites in neuronal cells. Energy deficits cause excessive depolarization of neuronal cells triggering glutamate-zinc evoked excitotoxic cascade. The intracellular zinc e...

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Dettagli Bibliografici
Pubblicato in:Neurochem Res
Autori principali: Szutowicz, Andrzej, Bielarczyk, Hanna, Zyśk, Marlena, Dyś, Aleksandra, Ronowska, Anna, Gul-Hinc, Sylwia, Klimaszewska-Łata, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2016
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357490/
https://ncbi.nlm.nih.gov/pubmed/28039593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-016-2154-z
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