The Regulatory Effects of Acetyl-CoA Distribution in the Healthy and Diseased Brain

Brain neurons, to support their neurotransmitter functions, require a several times higher supply of glucose than non-excitable cells. Pyruvate, the end product of glycolysis, through pyruvate dehydrogenase complex reaction, is a principal source of acetyl-CoA, which is a direct energy substrate in...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Ronowska, Anna, Szutowicz, Andrzej, Bielarczyk, Hanna, Gul-Hinc, Sylwia, Klimaszewska-Łata, Joanna, Dyś, Aleksandra, Zyśk, Marlena, Jankowska-Kulawy, Agnieszka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052899/
https://ncbi.nlm.nih.gov/pubmed/30050410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00169
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