Integrin CD11b activation drives anti-tumor innate immunity

Myeloid cells are recruited to damaged tissues where they can resolve infections and tumor growth or stimulate wound healing and tumor progression. Recruitment of these cells is regulated by integrins, a family of adhesion receptors that includes integrin CD11b. Here we report that, unexpectedly, in...

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Pubblicato in:Nat Commun
Autori principali: Schmid, Michael C., Khan, Samia Q., Kaneda, Megan M., Pathria, Paulina, Shepard, Ryan, Louis, Tiani L., Anand, Sudarshan, Woo, Gyunghwi, Leem, Chris, Faridi, M. Hafeez, Geraghty, Terese, Rajagopalan, Anugraha, Gupta, Seema, Ahmed, Mansoor, Vazquez-Padron, Roberto I., Cheresh, David A., Gupta, Vineet, Varner, Judith A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300665/
https://ncbi.nlm.nih.gov/pubmed/30568188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07387-4
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