A Small Molecule β2 Integrin Agonist Improves Chronic Kidney Allograft Survival by Reducing Leukocyte Recruitment and Accompanying Vasculopathy

Kidney allograft rejection is associated with infiltration of inflammatory CD11b+ leukocytes. A CD11b agonist leukadherin-1 (LA1) increases leukocyte adhesion, preventing their transmigration and tissue recruitment in vivo. Here, we test the extent to which LA1-mediated activation of CD11b/CD18 enha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Khan, Samia Q., Guo, Lingling, Cimbaluk, David J., Elshabrawy, Hatem, Faridi, Mohd Hafeez, Jolly, Meenakshi, George, James F., Agarwal, Anupam, Gupta, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291902/
https://ncbi.nlm.nih.gov/pubmed/25593918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2014.00045
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados