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Agonist Leukadherin-1 Increases CD11b/CD18-Dependent Adhesion Via Membrane Tethers
Integrin CD11b/CD18 is a key adhesion receptor that mediates leukocyte migration and immune functions. Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1. Here, we used single-molecule force spectroscopy to investigate the biophysica...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853324/ https://ncbi.nlm.nih.gov/pubmed/24314082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.020 |
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