Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Udgivet i:Front Microbiol
Main Authors: Machado, Diana, Lecorche, Emmanuel, Mougari, Faiza, Cambau, Emmanuelle, Viveiros, Miguel
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300501/
https://ncbi.nlm.nih.gov/pubmed/30619157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03072
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