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Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Podrobná bibliografie
Vydáno v:Front Microbiol
Hlavní autoři: Machado, Diana, Lecorche, Emmanuel, Mougari, Faiza, Cambau, Emmanuelle, Viveiros, Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300501/
https://ncbi.nlm.nih.gov/pubmed/30619157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03072
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