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Role of the Mmr Efflux Pump in Drug Resistance in Mycobacterium tuberculosis

Efflux pumps are membrane proteins capable of actively transporting a broad range of substrates from the cytoplasm to the exterior of the cell. Increased efflux activity in response to drug treatment may be the first step in the development of bacterial drug resistance. Previous studies showed that...

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Detalhes bibliográficos
Main Authors: Rodrigues, Liliana, Villellas, Cristina, Bailo, Rebeca, Viveiros, Miguel, Aínsa, José A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553716/
https://ncbi.nlm.nih.gov/pubmed/23165464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01482-12
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