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Role of the Mmr Efflux Pump in Drug Resistance in Mycobacterium tuberculosis

Efflux pumps are membrane proteins capable of actively transporting a broad range of substrates from the cytoplasm to the exterior of the cell. Increased efflux activity in response to drug treatment may be the first step in the development of bacterial drug resistance. Previous studies showed that...

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Bibliographic Details
Main Authors: Rodrigues, Liliana, Villellas, Cristina, Bailo, Rebeca, Viveiros, Miguel, Aínsa, José A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553716/
https://ncbi.nlm.nih.gov/pubmed/23165464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01482-12
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