Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Machado, Diana, Lecorche, Emmanuel, Mougari, Faiza, Cambau, Emmanuelle, Viveiros, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300501/
https://ncbi.nlm.nih.gov/pubmed/30619157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03072
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