In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

Context: Triptolide (TP) has outstanding biological activities, but it induces toxicities, particular hepatotoxicity, severely limiting its clinical application. Chlorogenic acid (CGA) has prominently medicinal and nutritional values. However, until now, it is not known whether CGA could mitigate TP...

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Veröffentlicht in:Pharm Biol
Hauptverfasser: Wang, Jun-Ming, Chen, Rong-Xing, Zhang, Lu-Lu, Ding, Ning-Ning, Liu, Chen, Cui, Ying, Cheng, Yong-Xian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300082/
https://ncbi.nlm.nih.gov/pubmed/31070533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2018.1527370
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