In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

Context: Triptolide (TP) has outstanding biological activities, but it induces toxicities, particular hepatotoxicity, severely limiting its clinical application. Chlorogenic acid (CGA) has prominently medicinal and nutritional values. However, until now, it is not known whether CGA could mitigate TP...

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Udgivet i:Pharm Biol
Main Authors: Wang, Jun-Ming, Chen, Rong-Xing, Zhang, Lu-Lu, Ding, Ning-Ning, Liu, Chen, Cui, Ying, Cheng, Yong-Xian
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300082/
https://ncbi.nlm.nih.gov/pubmed/31070533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2018.1527370
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