Activation of Nrf2 Protects against Triptolide-Induced Hepatotoxicity

Triptolide, the major active component of Tripterygium wilfordii Hook f. (TWHF), has a wide range of pharmacological activities. However, the toxicities of triptolide, particularly the hepatotoxicity, limit its clinical application. The hepatotoxicity of triptolide has not been well characterized ye...

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Autors principals: Li, Jia, Shen, Feihai, Guan, Cuiwen, Wang, Wenwen, Sun, Xiaozhe, Fu, Xinlu, Huang, Min, Jin, Jing, Huang, Zhiying
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079517/
https://ncbi.nlm.nih.gov/pubmed/24988078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100685
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