Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice

Oxidative stress and glutathione (GSH) depletion are implicated in mycocystin hepatotoxicity. To investigate the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in microcystin-induced liver injury, Nrf2-null, wild-type, and Keap1-hepatocyte knockout (Keap1-HKO) mice were treated with micr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lu, Yuan-Fu, Liu, Jie, Wu, Kai Connie, Qu, Qiang, Fan, Fang, Klaassen, Curtis D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965536/
https://ncbi.nlm.nih.gov/pubmed/24667526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093013
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker