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Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice
Oxidative stress and glutathione (GSH) depletion are implicated in mycocystin hepatotoxicity. To investigate the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in microcystin-induced liver injury, Nrf2-null, wild-type, and Keap1-hepatocyte knockout (Keap1-HKO) mice were treated with micr...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965536/ https://ncbi.nlm.nih.gov/pubmed/24667526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093013 |
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