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In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

Context: Triptolide (TP) has outstanding biological activities, but it induces toxicities, particular hepatotoxicity, severely limiting its clinical application. Chlorogenic acid (CGA) has prominently medicinal and nutritional values. However, until now, it is not known whether CGA could mitigate TP...

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Bibliographic Details
Published in:Pharm Biol
Main Authors: Wang, Jun-Ming, Chen, Rong-Xing, Zhang, Lu-Lu, Ding, Ning-Ning, Liu, Chen, Cui, Ying, Cheng, Yong-Xian
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300082/
https://ncbi.nlm.nih.gov/pubmed/31070533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2018.1527370
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