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A New Mechanism for Ribosome Rescue Can Recruit RF1 or RF2 to Nonstop Ribosomes

Bacterial ribosomes frequently translate to the 3′ end of an mRNA without terminating at an in-frame stop codon. In all bacteria studied to date, these “nonstop” ribosomes are rescued using trans-translation. Genes required for trans-translation are essential in some species, but other species can s...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Goralski, Tyler D. P., Kirimanjeswara, Girish S., Keiler, Kenneth C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299226/
https://ncbi.nlm.nih.gov/pubmed/30563899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02436-18
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