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Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication

Bacteria require at least one pathway to rescue ribosomes stalled at the ends of mRNAs. The primary pathway for ribosome rescue is trans-translation, which is conserved in >99% of sequenced bacterial genomes. Some species also have backup systems, such as ArfA or ArfB, which can rescue ribosomes...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Goralski, Tyler D. P., Dewan, Kalyan K., Alumasa, John N., Avanzato, Victoria, Place, David E., Markley, Rachel L., Katkere, Bhuvana, Rabadi, Seham M., Bakshi, Chandra Shekhar, Keiler, Kenneth C., Kirimanjeswara, Girish S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879415/
https://ncbi.nlm.nih.gov/pubmed/26953190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03089-15
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