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Development of a novel Francisella tularensis Live Vaccine Strain expressing ovalbumin provides insight into antigen-specific CD8(+) T cell responses

Progress towards a safe and effective vaccine for the prevention of tularemia has been hindered by a lack of knowledge regarding the correlates of protective adaptive immunity and a lack of tools to generate this knowledge. CD8(+) T cells are essential for protective immunity against virulent strain...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Place, David E., Williamson, David R., Yuzefpolskiy, Yevgeniy, Katkere, Bhuvana, Sarkar, Surojit, Kalia, Vandana, Kirimanjeswara, Girish S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746256/
https://ncbi.nlm.nih.gov/pubmed/29284034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190384
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