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Differing Effects of Interleukin-10 on Cutaneous and Pulmonary Francisella tularensis Live Vaccine Strain Infection

We investigated the role of interleukin-10 (IL-10) in cutaneous and pulmonary infection with Francisella tularensis. We found that after intradermal challenge of mice with the live vaccine strain (LVS) of F. tularensis, splenic IL-10 levels increased rapidly and reached a peak 5 days after infection...

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Autors principals: Metzger, Dennis W., Salmon, Sharon L., Kirimanjeswara, Girish
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676042/
https://ncbi.nlm.nih.gov/pubmed/23529615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00024-13
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