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Increased Susceptibility of IgA-Deficient Mice to Pulmonary Francisella tularensis Live Vaccine Strain Infection

Francisella tularensis, the causative agent of tularemia, is most deadly in the pneumonic form; therefore, mucosal immunity is an important first line of defense against this pathogen. We have now evaluated the lethality of primary F. tularensis live vaccine strain (LVS) pulmonary infection in mice...

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Autors principals: Furuya, Yoichi, Kirimanjeswara, Girish S., Roberts, Sean, Metzger, Dennis W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754209/
https://ncbi.nlm.nih.gov/pubmed/23836815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00408-13
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