Defective anti-polysaccharide IgG vaccine responses in IgA deficient mice

We report that IgA(−/−) mice exhibit specific defects in IgG antibody responses to various polysaccharide vaccines (Francisella tularensis LPS and Pneumovax), but not protein vaccines such as Fluzone. This defect further included responses to polysaccharide-protein conjugate vaccines (Prevnar and Ha...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Furuya, Yoichi, Kirimanjeswara, Girish S., Roberts, Sean, Racine, Rachael, Wilson-Welder, Jennifer, Sanfilippo, Alan M, Salmon, Sharon L, Metzger, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314215/
https://ncbi.nlm.nih.gov/pubmed/28774562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.07.071
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