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Detrimental Influence of Alveolar Macrophages on Protective Humoral Immunity during Francisella tularensis SchuS4 Pulmonary Infection

Opsonizing antibody is a critical component of the host protective immune response against many respiratory pathogens. However, the role of antibodies in protection against pulmonary infection with highly virulent Francisella tularensis strain SchuS4 is unclear, and the mechanism that allows F. tula...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Steiner, Donald J., Furuya, Yoichi, Metzger, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865038/
https://ncbi.nlm.nih.gov/pubmed/29311236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00787-17
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