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Detrimental Influence of Alveolar Macrophages on Protective Humoral Immunity during Francisella tularensis SchuS4 Pulmonary Infection

Opsonizing antibody is a critical component of the host protective immune response against many respiratory pathogens. However, the role of antibodies in protection against pulmonary infection with highly virulent Francisella tularensis strain SchuS4 is unclear, and the mechanism that allows F. tula...

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Опубликовано в: :Infect Immun
Главные авторы: Steiner, Donald J., Furuya, Yoichi, Metzger, Dennis W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865038/
https://ncbi.nlm.nih.gov/pubmed/29311236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00787-17
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